Characterization of long RNA therapeutics such as sgRNA and mRNA has led to new challenges for LC-MS analysts. One consideration is overcoming contemporary procedures that over digest RNA, losing sequence rich information in the process. Data interpretation and processing is often flagged as a major bottleneck, with manual confirmation becoming increasingly cumbersome as the RNA length increases.
Waters is committed to providing RNA scientists new tools to make RNA Characterization more accessible for gene therapy development. Looking for more information or need to discuss our latest application work?
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